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#6
Les médicaments contenant du modafinil peuvent ne pas être sûrs chez les personnes souffrant de problèmes cardiaques, d'épilepsie ou d'une maladie du foie. Le modafinil stimule les récepteurs cérébraux responsables de la libération de dopamine et de noradrénaline. Après les essais en Australie et en France, la société pharmaceutique française Euromedec a introduit Modalert à usage médical en 1994. Les National Institutes of Health des États-Unis notent que, bien que le Modafinil ait été étudié comme un éventuel activateur cognitif, des recherches supplémentaires sont nécessaires. Une étude a été menée sur une trentaine d'enfants présentant un trouble du spectre autistique. Le modafinil est un médicament délivré sur ordonnance. Le modafinil agit en augmentant la quantité d'un produit chimique (dopamine) qui est fabriqué et libéré dans le cerveau, et peut également fonctionner en modulant les zones du cerveau impliquées dans le cycle du sommeil. Le modafinil stimule le cerveau et augmente l'éveil chez les personnes atteintes de narcolepsie. Le médicament peut produire des effets secondaires dose-dépendants, y compris une déficience cognitive légère, qui comprend une diminution des performances aux tests de mémoire générale, d'attention et de concentration. C'est un dérivé de l'amphétamine et est vendu sous forme de pilule. Le modafinil est bien absorbé après administration orale, avec des concentrations sanguines maximales survenant 1 à 3 heures après l'ingestion. Le modafinil est considéré comme un promédicament et est activé dans le corps par des enzymes présentes dans le foie et l'estomac. Le modafinil a également été examiné dans le traitement de l'hypertrophie adéno-amygdalienne, de l'obésité et pour le traitement du trouble déficitaire de l'attention avec hyperactivité et des troubles du sommeil, y compris le trouble du rythme circadien, l'insomnie et l'apnée obstructive du sommeil. nootropique pharmacie Le modafinil a également des effets antihistaminiques et anticholinergiques. Il doit être pris avec de la nourriture. Le modafinil agit en augmentant l'activité des neurotransmetteurs qui aident le cerveau humain à contrôler la vigilance ou l'attention. Un nombre croissant de pharmacies sur Internet vendent du modafinil depuis l'étranger. Ce mécanisme est appelé «sommeil à ondes ultra-lente», dans lequel les neurones du cerveau sont plus excitables que dans un cycle de sommeil normal. L'état d'équilibre est atteint en 3 heures environ. L'activation des récepteurs de la dopamine se produit dans les régions dorsales du cerveau. En dehors du cerveau, le modafinil peut augmenter les niveaux d'hormone de croissance dans le sang, augmentant ainsi l'appétit et la masse grasse. La dose initiale recommandée de Modafinil est de 100 mg et la dose d'entretien est de 200 mg. Il a été conclu qu'il n'y avait pas suffisamment de preuves pour guider la pratique clinique.

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#7
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#8
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#9
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