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Le modafinil est un stimulant du système nerveux central. L'efficacité du modafinil peut être augmentée avec des doses plus élevées. Le modafinil est l'agent actif des formes disponibles dans le commerce de Provigil et de Ritalin. Le modafinil peut avoir un effet additif avec d'autres antidépresseurs chez les patients déprimés ou avec d'autres stimulants chez les narcoleptiques. Cependant, le modafinil a été associé à un temps de réaction accru dans les tâches complexes. Certaines de ces réactions peuvent être dose-dépendantes et prévisibles. Cette augmentation rend plus de dopamine disponible dans la fente synaptique et augmente l'excitation neurale, ce que Modafinil est conçu pour faire. Bien que le mécanisme exact de son action ne soit pas clair, on pense principalement qu'il stimule directement un récepteur de la sérotonine dans le cerveau. Le modafinil est bien toléré, avec certains effets secondaires courants, notamment des maux de tête, des troubles du sommeil et des nausées. C'est pourquoi le modafinil est connu pour provoquer une hypomanie (par exemple, se sentir énergique, bavard et exalté), mais également provoquer de l'insomnie (par exemple, être incapable de s'endormir). Le modafinil est bien absorbé après administration orale. On pense que le modafinil crée moins de tolérance que la caféine. modafinil europe Des études cliniques chez l'adulte et l'enfant ont montré que le modafinil a un effet sur le sommeil et l'éveil. Le récepteur alpha-2 est présent dans les ganglions de la base, mais le modafinil ne semble pas produire d'effets semblables à ceux de la maladie de Parkinson chez les rongeurs et n'empêche pas le comportement stéréotypique induit par la dopamine. Le modafinil ne doit pas être utilisé chez les femmes enceintes ou allaitantes et doit être pris avec prudence avec les anticoagulants. Le modafinil peut augmenter les niveaux d'autres médicaments métabolisés (décomposés en substances sans fonction connue) tels que la théophylline, la sulfaméthazine et le vinolactame. Le modafinil est discuté dans la recherche sur les agents favorisant l'éveil depuis plusieurs décennies. Le modafinil est généralement utilisé pour les troubles qui sollicitent l'attention ou la concentration. Les effets secondaires du modafinil peuvent varier d'une personne à l'autre et résulter de sa nature de médicament stimulant. Le modafinil peut également être prescrit par les neurologues pour traiter les troubles du sommeil tels que la narcolepsie. Sur la base des effets secondaires les plus courants, la dose ne doit pas dépasser 400 mg (2-3 comprimés). Le modafinil est un sous-produit de la synthèse chimique et peut coûter très cher, plus de 400 dollars américains pour un seul comprimé de 100 mg. Le modafinil peut interagir avec les IMAO et les ISRS. Les effets secondaires courants comprennent les maux de tête, les troubles du sommeil, les nausées et la nervosité. Le modafinil est le nom de marque des médicaments nootropes qui ont fait la une des journaux ces dernières années. Il contient les mêmes ingrédients actifs et le même niveau de concentration que le médicament d'origine. Le modafinil appartient à une classe de médicaments appelés agents favorisant l'éveil, qui stimulent le SNC pour augmenter l'éveil.

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