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06-21-2023, 05:05 PM
(This post was last modified: 06-21-2023, 05:06 PM by Le Modafinil .)
Les observations initiales avec le mГ©dicament comme traitement de la narcolepsie ont Г©tГ© faites en France en 1987, puis confirmГ©es par des scientifiques de l'UniversitГ© du Kentucky en 1993. C'est Г©galement un traitement de classe 1 pour le trouble dГ©ficitaire de l'attention avec hyperactivitГ© (TDAH). C'est un mГ©lange racГ©mique de deux isomГЁres optiques, ®- et (S)-modafinil. C'est la forme qui devient Г©ventuellement disponible pour la liaison avec les transporteurs de la dopamine et de la noradrГ©naline, ainsi qu'avec le transporteur de la sГ©rotonine. Il doit ГЄtre interrompu si l'individu Г©prouve une somnolence extrГЄme. Le modafinil doit ГЄtre utilisГ© avec prudence chez les personnes souffrant de maladies cardiovasculaires, car la somnolence peut entraГ®ner une conduite dangereuse. Au Royaume-Uni, la dose recommandГ©e est de 200 mg deux fois par jour. Le modafinil est disponible sur ordonnance auprГЁs d'un certain nombre de fournisseurs de soins mГ©dicaux aux Г‰tats-Unis. Le modafinil se prГ©sente sous la forme d'une formulation Г particules fines. Cela lui confГЁre des propriГ©tГ©s stimulantes, ou des propriГ©tГ©s d'excitation, et peut garder les gens alertes.
acheter du modafinil On pense que le modafinil aide le cerveau Г arrГЄter la production de dopamine la nuit et Г activer la production de dopamine pendant la journГ©e. En fait, pour ceux qui peuvent ГЄtre attentifs, il y a de fortes chances qu'ils aient pris du Modafinil sans aucun problГЁme et qu'ils soient prГЄts Г partager leur histoire. Il agit comme un stimulant au niveau du rГ©cepteur de la dopamine D3 ; cet effet est le mГЄme que celui d'une amphГ©tamine entiГЁrement synthГ©tique. Jouvet a Г©tudiГ© le modafinil dans des essais cliniques Г l'UniversitГ© de Paris. Il est vendu comme mГ©dicament en vente libre aux Г‰tats-Unis. De plus, le modafinil peut provoquer des rГ©actions allergiques graves telles que l'anaphylaxie et le syndrome de Stevens-Johnson, qui surviennent gГ©nГ©ralement chez les personnes sensibles et sont gГ©nГ©ralement bГ©nignes. Au fil des ans, il y a eu un certain nombre d'effets secondaires associГ©s au modafinil. Le modafinil est un stimulant du SNC. Modafinil a Г©tГ© testГ© dans un certain nombre de groupes de sujets contrГґlГ©s par placebo, randomisГ©s, en double aveugle, contrГґlГ©s par placebo et indГ©pendants. Peut augmenter le risque de convulsions chez les personnes ayant des antГ©cГ©dents de troubles convulsifs (Effets secondaires du modafinil). Comme d'autres mГ©dicaments de cette classe, le modafinil agit en modifiant les niveaux de certains neurotransmetteurs dans le cerveau. Il est donc important de prendre ce mГ©dicament Г un moment oГ№ il est peu probable que le patient ait oubliГ© une dose. Le modafinil est le nom d'un inhibiteur sГ©lectif et rГ©versible de la recapture de la noradrГ©naline (NET).
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La plupart des gens, cependant, ont tendance Г prendre 50 mg et peuvent rester Г©veillГ©s pendant un maximum de six heures. La plupart des recherches ont Г©tГ© dirigГ©es vers les personnes souffrant de troubles du sommeil et ont montrГ© que le modafinil augmente la vigilance, amГ©liore la mГ©moire et rГ©duit le temps nГ©cessaire pour s'endormir. Il est maintenant Г©galement utilisГ© comme somnifГЁre non mГ©dical. Il est produit par GlaxoSmithKline, mais la sociГ©tГ© ne dГ©tient pas le brevet. Comme d'autres stimulants, l'efficacitГ© du modafinil est maximale lorsqu'il est utilisГ© comme thГ©rapie pour traiter les problГЁmes de sommeil. Le modafinil est utilisГ© dans le traitement de la somnolence excessive due Г la narcolepsie et aux troubles du sommeil liГ©s au travail postГ© et pour augmenter l'Г©veil chez les personnes souffrant d'apnГ©e obstructive du sommeil. Une mГ©ta-analyse de ces essais a suggГ©rГ© que le modafinil est un traitement efficace pour l'amГ©lioration cognitive chez les personnes en bonne santГ©. Il se lie au В« rГ©cepteur de la vitamine D3 В» ou VDR. Modafinil Modafinil R (gГ©nГ©rique) et d'autres noms pour le modafinil incluent Provigil, Alertec Modafinil, Provigil 100, Vigil et Modafinil-100. Il a une demi-vie d'environ 4 Г 6 heures lorsqu'il est pris par voie orale. Le modafinil est fabriquГ© aux Г‰tats-Unis par Novartis sous forme de comprimГ© Г des doses de 100 Г 200 mg. ГЂ des niveaux Г©levГ©s, la dopamine peut provoquer des effets secondaires.
acheter du modafinil Des doses aussi faibles que 75 mg ont montrГ© des effets thГ©rapeutiques. Armodafinil se lie au transporteur a-amino-adipate (AAT) qui rГ©gule le transport de la dopamine. Le modafinil agit en activant les neurotransmetteurs et les neurorГ©cepteurs. Les patients d'une Г©tude clinique ont connu une amГ©lioration de la vigilance et de l'Г©veil en huit Г neuf heures, par rapport au placebo. Le modafinil est un stimulant cГ©rГ©bral, c'est-Г -dire une substance qui affecte le cerveau ou le systГЁme nerveux central. Il est Г©galement utilisГ© hors AMM pour aider Г augmenter la productivitГ© chez les personnes ayant une mauvaise qualitГ© de sommeil. Le traitement au modafinil a augmentГ© le temps entre les Г©pisodes de sommeil lorsque les souris seraient normalement au repos et ne dormaient pas. Le modafinil est insoluble dans l'eau, mais soluble dans l'Г©thanol. En effet, la posologie de modafinil peut ГЄtre ajustГ©e en fonction de votre efficacitГ©, et les personnes peuvent obtenir une augmentation illicite de leurs doses lorsqu'elles ressentent des effets secondaires. Environ 20 % sont excrГ©tГ©s sous forme de modafinil non mГ©tabolisГ©.
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