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La dose initiale recommandГ©e est de 75 Г  100 mg ; la dose maximale recommandГ©e est de 300 mg, les doses thГ©rapeutiques Г©tant comprises entre 200 et 400 mg. Le modafinil n'est pas addictif. La dose adulte habituelle de modafinil est de 200 Г  400 mg/jour. Dans les Г©tudes animales, il a Г©tГ© dГ©montrГ© qu'il amГ©liore l'apprentissage et la mГ©moire, mais pas chez les humains. Le modafinil est Г©galement distinct des mГ©thylxanthines, telles que la cafГ©ine et la thГ©ophylline, ainsi que des amphГ©tamines. Le mГ©dicament prend gГ©nГ©ralement effet dans les 45 Г  60 minutes. Le traitement peut Г©galement rГ©duire les symptГґmes du trouble du sommeil liГ© au travail postГ©. La substance est principalement un inhibiteur de la recapture de la dopamine et de la noradrГ©naline. Le modafinil agit en favorisant la libГ©ration de dopamine dans les centres du plaisir du cerveau (noyau accumbens et caudГ©), tout en inhibant la recapture de la dopamine, ce qui lui donne pour effet d'augmenter les niveaux de dopamine. Dans tous les cas, la dose peut varier, mais la gamme de doses habituelles pour le modafinil est de 400 Г  600 mg (ou de 200 Г  300 mg pour les versions Г  libГ©ration prolongГ©e), selon l'indication pour laquelle il est utilisГ©. Le modafinil peut provoquer des maux de tГЄte et d'autres effets secondaires, tels que des nausГ©es ou des Г©tourdissements. Il est gГ©nГ©ralement utilisГ© pour ceux qui ont de mauvais cycles veille-sommeil. Le modafinil a Г©tГ© commercialisГ© sous les noms de Vigil, Alertec et Provigil. Les complГ©ments alimentaires liГ©s au modafinil comprennent le mГ©dicament sur ordonnance. Le modafinil est utilisГ© pour traiter la cataplexie, la paralysie du sommeil et la somnolence excessive associГ©e Г  la narcolepsie, et il s'est Г©galement avГ©rГ© efficace pour rГ©duire la frГ©quence des crises de sommeil lorsqu'il est utilisГ© avec des antihistaminiques H1. acheter du modafinil Il est conseillГ© aux patients souffrant d'affections qui abaissent la tension artГ©rielle, telles que l'hypertension, de rГ©duire d'abord leur dose de mГ©dicament et de consulter leur mГ©decin avant de l'augmenter. H20) et appartient Г  la classe des stimulants connus sous le nom de benzazГ©pines. Nous ne serons pas tenus responsables des dommages causГ©s par les personnes qui achГЁtent du modafinil auprГЁs de fournisseurs tiers non autorisГ©s, bien que les chances que cela se produise soient faibles. C'est un stimulant du systГЁme nerveux central qui augmente l'Г©veil et amГ©liore les performances cognitives. MГ©dicaments tels que alprazolam, alcool, antihistaminiques, atomoxГ©tine, atropine, carbamazГ©pine, clomipramine, clonidine, clozapine, codГ©ine, dexchlorphГ©niramine, divalproex, doxГ©pine, fluoxГ©tine, hydroxyzine, itraconazole, lГ©vГ©tiracГ©tam, mexilГ©tine, midazolam, paroxГ©tine, phГ©nobarbital, phГ©nytoГЇne, prazosine, primidone , la rispГ©ridone, la sertraline, la thioridazine, le triazolam, la trazodone, le tГ©mazГ©pam, les antidГ©presseurs tricycliques, la trimipramine, le zaleplon, la benztropine et les corticostГ©roГЇdes peuvent augmenter le risque de convulsions et doivent ГЄtre utilisГ©s avec prudence si vous avez des antГ©cГ©dents de convulsions ou si vous prenez des mГ©dicaments antiГ©pileptiques. Il est Г©galement prescrit par les mГ©decins pour traiter l'apnГ©e obstructive du sommeil (AOS) lorsque les autres traitements n'ont pas fonctionnГ©. Aux Г‰tats-Unis, il s'agit d'un mГ©dicament approuvГ© pour le traitement de la somnolence excessive associГ©e aux troubles du sommeil liГ©s au travail postГ© et pour le traitement de la somnolence associГ©e Г  l'apnГ©e obstructive du sommeil. Il est Г©galement utilisГ© comme traitement d'appoint dans la prise en charge de la somnolence excessive associГ©e Г  la narcolepsie et des troubles chroniques du sommeil dus au travail postГ©, au dГ©calage horaire ou au sevrage du modafinil. Le modafinil bloque Г©galement la recapture des amines biogГЁnes dopamine, noradrГ©naline et sГ©rotonine, ce qui permet une libГ©ration accrue de ces neurotransmetteurs au niveau des synapses. Le modafinil est contre-indiquГ© chez les personnes ayant des antГ©cГ©dents d'hypersensibilitГ© au modafinil et Г  ses constituants. La quantitГ© d'acГ©tylcholine libГ©rГ©e est augmentГ©e en consГ©quence, ce qui entraГ®ne une augmentation des niveaux de vigilance et d'Г©veil. Le modafinil peut ГЄtre plus efficace pour amГ©liorer la qualitГ© du sommeil que pour augmenter le temps d'Г©veil.

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On ne sait pas si le modafinil est un agoniste ou un antagoniste des récepteurs de l'adénosine. Aux États-Unis, il est disponible auprès des médecins sous forme orale sous forme de comprimés, de gélules ou de liquide. Le modafinil est considéré comme un promédicament et est activé dans le corps par des enzymes présentes dans le foie et l'estomac. Les effets secondaires les plus fréquemment signalés du traitement par le modafinil pour le TDAH comprennent les maux de tête, les troubles du sommeil et la nervosité. Il a été breveté en 1976 et a été approuvé pour un usage médical aux États-Unis en 1998. L'efficacité est plus importante chez les patients ayant une forte tendance au sommeil. Certains médecins considèrent cela comme un produit avec un manque d'efficacité prouvée pour un agent d'amélioration cognitive et ont déconseillé son utilisation en tant qu'amplificateur cognitif. Modafinil Purchase est la marque de modafinil la plus populaire aux États-Unis. L'utilisation du modafinil doit être limitée à 6 heures maximum par jour. Le modafinil a une longue demi-vie de 10 à 14 heures. Le modafinil agit en augmentant l'éveil et en améliorant la mémoire. Il fournit une libération prolongée pouvant durer jusqu'à 12 heures et présente des propriétés pharmacocinétiques similaires à celles du modafinil. Les effets durent jusqu'à 24 heures, avec des effets maximaux survenant après 2 à 3 heures. La somnolence est causée par une carence en hypocrétine, un neurotransmetteur neuropeptide. acheter du modafinil On ne sait pas si le modafinil présente des avantages par rapport aux stimulants pharmaceutiques, tels que le méthylphénidate, pour améliorer la concentration et la mémoire. Il s'agit d'une drogue synthétique dont la structure chimique est liée à la classe des stimulants amphétamines et qui est utilisée en clinique depuis les années 1970. Le modafinil se prend par voie orale, souvent avec une boisson énergisante ou du café. Aux États-Unis, le modafinil est approuvé par la FDA pour le traitement de la somnolence diurne excessive, ou connue sous le nom de narcolepsie, chez les adultes et les enfants de 10 ans et plus. En 2002, l'agence française de protection des consommateurs a examiné deux recours collectifs contre deux fabricants de modafinil, dénonçant le traitement comme un médicament commercialisé sans prescription médicale. Il ne doit pas être utilisé comme substitut du sommeil. Le modafinil semble agir en agissant sur la dopamine et en modulant les zones du cerveau impliquées dans le cycle du sommeil. Il se lie au site actif du transporteur de recapture de la dopamine. Il a été démontré qu'il s'agit d'un médicament relativement sûr, avec peu ou pas d'effets secondaires négatifs. Ce médicament affecte plusieurs sites du cerveau qui jouent un rôle dans le sommeil, sans affecter de manière significative les autres parties du cerveau. Ces substances agissent sur le cerveau pour vous aider à rester éveillé.

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