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#7
Au dГ©pГґt, le mГ©dicament est administrГ© par injection sous-cutanГ©e toutes les deux semaines. Le nom chimique est 2-(benzhydrylsulfinyl)acГ©tone. п»їLe modafinil est fabriquГ© sous forme de poudre cristalline blanche ou beige clair Г  blanc cassГ©. Les effets secondaires rares et graves peuvent inclure des rГ©actions allergiques telles que l'anaphylaxie et le syndrome de Stevens-Johnson, ainsi que des hallucinations chez les personnes ayant des antГ©cГ©dents de psychose. Il se prГ©sente sous plusieurs formes, telles que des gГ©lules, des comprimГ©s ou des sirops. La posologie est gГ©nГ©ralement prise vers 9 heures du matin et le traitement peut durer quelques mois pour un patient. Il fait partie de la classe de mГ©dicaments modafinil, ou dГ©rivГ©s du modafinil, et est un stimulant du SNC de longue durГ©e et non sГ©lectif. Cela favorise la libГ©ration de noradrГ©naline et de dopamine. L'acide libre de modafinil est l'ingrГ©dient actif de Provigil et il est plus difficile Г  trouver au Royaume-Uni et ailleurs. Il est cependant trГЁs efficace pour traiter la somnolence diurne excessive associГ©e Г  la narcolepsie et Г  l'apnГ©e obstructive du sommeil, qui peuvent toutes deux entraГ®ner des consГ©quences mГ©dicales nГ©fastes importantes telles que des accidents de la route et du travail. Il y a actuellement un manque de donnГ©es publiГ©es sur l'utilisation du modafinil pour une utilisation Г  court terme et sur l'utilisation chez les patients pГ©diatriques, gГ©riatriques et enceintes. Le modafinil a Г©tГ© approuvГ© par la Food and Drug Administration (FDA) des Г‰tats-Unis au Canada et par la Medicine and Healthcare Products Regulatory Agency (MHRA) au Royaume-Uni. Il est assez rapidement absorbГ© lorsqu'il est pris par voie orale, mais a un index thГ©rapeutique Г©troit en raison du risque accru d'effets secondaires Г  des doses plus Г©levГ©es. Le modafinil peut ГЄtre utilisГ© pour traiter un certain nombre de troubles du sommeil, notamment la narcolepsie, l'apnГ©e du sommeil, les troubles du sommeil liГ©s au travail postГ© et autres. Mais, son efficacitГ© dans le traitement de toute condition autre que les troubles primaires du sommeil reste Г  prouver. modafinil en ligne Le modafinil a Г©galement des effets antihistaminiques et anticholinergiques. Son efficacitГ© est similaire Г  celle des amphГ©tamines, qui stimulent Г  la fois les systГЁmes noradrГ©nergique et dopaminergique. Il existe de nombreuses Г©tudes animales et humaines indiquant que le modafinil peut amГ©liorer le fonctionnement cognitif. Il agit Г©galement en stimulant directement les rГ©cepteurs de l'orexine dans le cerveau. La dose la plus efficace dГ©pend de la personne traitГ©e et peut varier en fonction de la cause sous-jacente de la somnolence, de l'Гўge, du sexe, du poids corporel et d'autres facteurs. Le modafinil, souvent appelГ© Provigil, est un mГ©dicament utilisГ© pour traiter la somnolence causГ©e par l'apnГ©e du sommeil et les troubles du travail postГ© chez les personnes qui effectuent rГ©guliГЁrement des quarts de nuit. Une substance similaire, l'amphГ©tamine, avait dГ©jГ  Г©tГ© utilisГ©e comme stimulant dans les annГ©es 1970 par des chercheurs en toxicomanie, et le Modafinil a Г©tГ© dГ©veloppГ© pour ГЄtre 10 fois moins stimulant. On ne sait toujours pas si les personnes qui utilisent Modafinil Г  cette fin prennent effectivement un mГ©dicament sur ordonnance. Aux Г‰tats-Unis, le modafinil est approuvГ© comme agent favorisant l'Г©veil pour les personnes souffrant de narcolepsie, de troubles du sommeil liГ©s au travail postГ© et d'apnГ©e du sommeil. Le modafinil est un stimulant du systГЁme nerveux central (SNC) utilisГ© pour traiter la somnolence due Г  la narcolepsie, les troubles du sommeil liГ©s au travail postГ© et l'apnГ©e obstructive du sommeil.

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Il est bien toléré et peut être utilisé en toute sécurité pendant la grossesse. Il a également des effets secondaires possibles tels que des étourdissements, des nausées ou des maux de tête. Le modafinil est un antidépresseur stimulant approuvé pour la vente aux États-Unis depuis le 15 février 1998. En tant que médicament sur ordonnance disponible dans plus de 60 pays, le modafinil est considéré comme sûr, mais les professionnels de la santé doivent être vigilants lorsqu'ils le prescrivent à des personnes ayant des antécédents personnels de psychose, d'arythmie, d'hypertension, d'insuffisance rénale ou hépatique ou de problèmes cardiaques. Le nom commercial Modafinil est une marque déposée de la société pharmaceutique française, le pharma, dont le siège est à Lille, en France. L'action du modafinil vise principalement la voie des récepteurs de l'orexine du cerveau, qui est une voie qui contrôle l'éveil. Comme d'autres médicaments stimulants, le modafinil augmente les niveaux de dopamine (l'un des produits chimiques présents dans le cerveau qui envoie des messages chimiques au reste du corps) et de noradrénaline (un autre produit chimique dans le cerveau, qui, entre autres, ralentit le corps). Le modafinil semble avoir peu d'effets secondaires, les effets secondaires les plus fréquemment signalés étant les maux de tête, les nausées et la somnolence. Le modafinil est considéré comme un traitement de deuxième intention pour ces troubles, ce qui signifie qu'il est utilisé à la place de médicaments qui agissent plus rapidement ou avec moins d'effets secondaires, tels que l'amphétamine et d'autres stimulants centraux. Le modafinil peut agir sur d'autres substances qui interagissent avec la dopamine, telles que les récepteurs de la sérotonine. Il est indiqué pour améliorer l'éveil jusqu'à 24 heures chez les personnes atteintes de narcolepsie, de troubles du sommeil liés au travail posté et chez celles qui ont des difficultés à rester éveillées lorsqu'elles utilisent des machines ou effectuent un travail posté. Aux États-Unis, le modafinil est approuvé pour le traitement de la somnolence excessive causée par la narcolepsie et les troubles du sommeil liés au travail posté chez les adultes. Le mécanisme exact par lequel le modafinil affecte le sommeil n'est pas clair. modafinil en ligne Le modafinil peut également stimuler les récepteurs bêta-adrénergiques. Le modafinil est une poudre cristalline blanche à blanc cassé et est généralement stable jusqu'à six mois s'il est conservé comme recommandé. Nous ne serons pas tenus responsables des dommages causés par les personnes qui achètent du modafinil auprès de fournisseurs tiers non autorisés, bien que les chances que cela se produise soient faibles. Dans la plupart des cas, ces interactions sont légères et ne nécessitent pas d'ajustement de votre dose de modafinil. Une étude qui avait un aspect de performance a trouvé des avantages similaires dans l'amélioration des performances de la mémoire, de la vigilance et de la créativité. La FDA n'a pas mené sa propre méta-analyse d'essais contrôlés randomisés (ECR), mais s'est plutôt appuyée sur les résultats des ECR publiés. C'est la libération contrôlée de Modafinil qui est utile pour augmenter l'éveil jusqu'à la journée, sans les effets secondaires désagréables tels que les maux de tête dont certains utilisateurs se plaignent avec le Modafinil à libération immédiate. Le modafinil est un agent d'amélioration cognitive efficace qui dure environ 12 à 16 heures. Depuis, les utilisations hors AMM se sont développées, comme en témoigne cette étude. Les effets secondaires peuvent s'aggraver à mesure que la tolérance s'installe. Modafinil peut être utilisé avec ou sans nourriture.

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#8
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#9
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