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Les effets secondaires courants comprennent la somnolence, les maux de tГЄte, les nausГ©es et les troubles du sommeil. Le modafinil est un promГ©dicament dimГЁre cyclique du 2-(diphГ©nylmГ©thoxy)phГ©nylacГ©tamide. Le modafinil agit pour inhiber la recapture de la dopamine et de la noradrГ©naline, provoquant ainsi une augmentation de leur concentration et une augmentation de l'Г©veil. En France, il est commercialisГ© sous la marque Rapiflor. Le modafinil est un mГ©dicament destinГ© Г vous aider Г fonctionner de maniГЁre trГЁs importante. On pense que cet effet est dГ» au fait que le modafinil amГ©liore la mГ©moire de travail et la flexibilitГ© cognitive. Le prendre en continu au fil du temps a produit des rГ©sultats mitigГ©s. Le prendre le soir peut vous faire vous sentir trop fatiguГ© pour vous endormir. Par consГ©quent, il aide Г stimuler les neurones et les cellules nerveuses du cerveau. Il a Г©tГ© dГ©montrГ© que l'utilisation hors AMM chez les humains et les animaux augmente la vigilance et amГ©liore le rappel de la mГ©moire. Modiodal Lorsqu'il est pris Г la mГЄme heure chaque jour, le mГ©dicament peut interfГ©rer avec le cycle du sommeil et perturber le rythme circadien normal du corps. Il existe plusieurs formes posologiques diffГ©rentes; cependant, il a Г©tГ© constatГ© que les doses varient considГ©rablement dans le traitement de troubles du sommeil spГ©cifiques. Il peut Г©galement ГЄtre utilisГ© comme stimulant cognitif pour ceux qui souffrent de "brouillard cГ©rГ©bral". L'affinitГ© du mГ©dicament pour les rГ©cepteurs de la dopamine est jusqu'Г 200 fois supГ©rieure Г celle de l'amphГ©tamine, qui est la substance utilisГ©e pour traiter la narcolepsie. La dose quotidienne maximale peut ГЄtre doublГ©e chez les patients ayant un indice de masse corporelle supГ©rieur Г 40. Ce mГ©canisme est impliquГ© dans la rГ©gulation de la concentration de dopamine dans la synapse en limitant le taux de recapture de dopamine vers le neurone prГ©synaptique. Le modafinil est gГ©nГ©ralement bien tolГ©rГ©, avec des effets secondaires possibles, notamment des maux de tГЄte, des troubles du sommeil et des nausГ©es. Le modafinil est susceptible d'augmenter les niveaux extracellulaires de dopamine dans la zone tegmentale ventrale du mГ©sencГ©phale, agissant pour activer les rГ©cepteurs de la dopamine sur les Г©pines D2 (dopamine-2). C'est une poudre cristalline blanche Г blanc cassГ© ou incolore. Le constituant actif du modafinil est un inhibiteur de la recapture de la noradrГ©naline-dopamine. Ces marques possГЁdent toutes exactement la mГЄme prescription. Il est gГ©nГ©ralement utilisГ© Г des doses de 50 Г 200 mg prises le matin. L'arrГЄt est recommandГ© dГЁs les premiers signes d'Г©ruption cutanГ©e ou de rГ©actions similaires.
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