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Aux États-Unis, il est disponible en comprimé de 100 mg. L'ingrédient actif du modafinil est la vigilance chez les personnes atteintes de narcolepsie et l'éveil chez les personnes souffrant de troubles du sommeil liés au travail posté. On pense que le modafinil a des effets favorisant l'éveil par les mécanismes suivants : Le modafinil est un médicament délivré sur ordonnance (autorisé au Royaume-Uni) développé dans les années 1970 par la société pharmaceutique française Academia et les laboratoires Lafon, pour le traitement de la narcolepsie et de l'insomnie du travail posté. Le modafinil, qui se lie également aux récepteurs de l'adénosine A1, agit en bloquant ces récepteurs, ce qui entraîne une augmentation des niveaux d'AMPc dans le cerveau. Il s'agit d'un médicament d'ordonnance qui doit être acheté dans une pharmacie plutôt que dans une grande chaîne de magasins. Il est généralement pris avec de la nourriture. Le principal ingrédient pharmaceutique actif du modafinil est le N-acétyl-d-aspartyl-d-glutamate (NAAG), bien que la concentration exacte de cet ingrédient ne soit pas connue. Le modafinil produit ses principaux effets psychoactifs en se liant aux molécules de transport de la recapture de la sérotonine dans les terminaisons nerveuses du cerveau. Le modafinil ne doit pas être pris avec des dépresseurs du SNC tels que le carisoprodol. Il est important de noter que la National Sleep Foundation définit quatre catégories de somnolence : L'utilisation du modafinil est approuvée aux États-Unis par la Food and Drug Administration (FDA) des États-Unis pour traiter la narcolepsie, les troubles du sommeil liés au travail posté et l'apnée obstructive du sommeil. Provigil Achat Comme l'amphétamine, c'est un stimulant non amphétamine. Cela doit être divisé en 2 doses égales prises toutes les 12 heures. La dose habituelle de modafinil varie d'une personne à l'autre en raison des différences de constitution génétique et de métabolisme. La dopamine est un produit chimique qui envoie des informations à d'autres parties du cerveau. Modulation du système sérotoninergique Le modafinil agit comme un stimulant du système nerveux central, d'abord dans le locus coeruleus du cerveau, puis dans les parties plus distales du cerveau, améliorant l'activité du système sérotoninergique. Le modafinil est disponible uniquement au Royaume-Uni en tant que médicament délivré uniquement sur ordonnance sous le nom commercial Provigil. Le modafinil ne produit pas les mêmes effets que les amphétamines, qu'il convient d'éviter. Le modafinil se lie également à la sous-unité alpha-4 du récepteur nicotinique de l'acétylcholine, et donc indirectement à plusieurs récepteurs dont le récepteur dopaminergique D4, le récepteur sérotonine-2 et 5-HT7 et le récepteur nicotinique de l'acétylcholine. Il est recommandé aux personnes prenant du Modafinil de constater une amélioration significative de leur capacité à rester éveillé. Il est principalement utilisé pour le traitement de la narcolepsie, des troubles du sommeil liés au travail posté et de l'apnée obstructive du sommeil. Le médicament n'a cependant pas l'effet inverse, car toute augmentation des niveaux d'activité génère une sensation de fatigue.
Acheter Provigil Generique Nootropique En France Modafinil En Ligne Sans Ordonnance Provigil En Maroc Modiodal Drogue c050749
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