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01-09-2023, 10:06 PM
(This post was last modified: 01-09-2023, 10:07 PM by Modafinil 200.)
À ce jour, aucun bénéfice cliniquement significatif n'a été démontré pour l'utilisation du modafinil chez les adultes en bonne santé. Le modafinil est un stimulant unique qui est une substance favorisant l'éveil lorsqu'il est utilisé comme médicament d'appoint pour les troubles de la somnolence, tels que la narcolepsie et les troubles du sommeil liés au travail posté. Les personnes souffrant de troubles du sommeil peuvent bénéficier du modafinil car c'est un stimulant qui aide les gens à se réveiller plus rapidement. Le grand comprimé de 100 mg peut être dissous dans de l'eau et pris à jeun avant un repas ou sous la langue. Filocomo, un avocat de New York, qui a créé New River Pharmaceuticals. Les comprimés de modafinil contiennent une forme à libération prolongée du médicament (120 mg, 200 mg et 400 mg), avec le même médicament, le modafinil, dans chaque comprimé. La société fournit le médicament, fabriqué par Sun Pharma, à des fins non conformes telles que le traitement du syndrome de fatigue chronique, de la douleur chronique, des troubles du travail posté et de la narcolepsie. Provigil En France Le modafinil est très efficace dans le traitement d'un large éventail de troubles du sommeil. Une capsule contenant du modafinil est disponible, mais n'est pas une formulation typique utilisée dans les études sur son efficacité. Dans les études animales, le modafinil a amélioré l'éveil et la mémoire altérée, et s'est avéré efficace dans des tâches plus complexes. Certaines sociétés pharmaceutiques tentent de commercialiser le modafinil comme médicament pour l'amélioration cognitive, en particulier pour les étudiants d'âge collégial, dans le cadre d'une étude. Le modafinil est un stimulant du système nerveux central utilisé pour aider les personnes souffrant de privation de sommeil. Le modafinil est utilisé pour traiter la somnolence due à la narcolepsie, les troubles du sommeil liés au travail posté et l'apnée obstructive du sommeil. Dans le SNC, cela n'affectera probablement que les neurones qui ont été précédemment activés par l'acétylcholine. La quantité prise doit être ajustée en fonction de la quantité de modafinil dont le patient a besoin et chez les personnes souffrant d'une maladie cardiaque grave telle qu'une insuffisance cardiaque. Il n'a pas été étudié à d'autres fins, y compris le trouble déficitaire de l'attention (ADD) et le trouble déficitaire de l'attention avec hyperactivité (TDAH). Le modafinil est généralement indiqué pour le traitement de la somnolence associée à la narcolepsie, l'hypersomnie idiopathique, les troubles du sommeil liés au travail posté et le syndrome d'apnée obstructive du sommeil. Il a également été étudié pour voir s'il peut améliorer l'attention et la mémoire des personnes atteintes de trouble déficitaire de l'attention/hyperactivité, et s'il peut traiter des conditions telles que le syndrome de fatigue chronique.
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Sa demi-vie est d'environ 3 à 5 heures et son métabolisme est très lent. Il a également été utilisé pour améliorer la cognition chez les personnes présentant des déficits, à la fois chez les personnes atteintes d'un trouble déficitaire de l'attention avec hyperactivité (TDAH) et chez les personnes âgées. À l'époque, on pensait que le composé était un agoniste des récepteurs de la dopamine, mais il s'est avéré plus tard qu'il s'agissait d'un antagoniste des récepteurs de la dopamine non D1 et non D2. Le modafinil est un médicament qui a été développé par des scientifiques pour aider les gens à rester éveillés. Introduit pour la première fois en 1994, le modafinil est un nootropique qui a été initialement conçu pour être utilisé pour traiter la narcolepsie et les troubles du sommeil liés au travail posté. Provigil En France Le modafinil est un inhibiteur actif, sélectif et réversible du transporteur de la dopamine. Le modafinil est un médicament racémique, un mélange d'isomères droit et gauche. Un comprimé de 250 mg existe, mais celui-ci contient généralement 250 mg de modafinil et 125 mg d'un antihistaminique. La forme la plus courante de modafinil est l'énantiomère R du méthylphénidate, un dérivé de l'amphétamine. Le modafinil est soluble dans l'eau, l'éthanol et le méthanol. Le modafinil peut réduire la somnolence dans le cerveau pendant huit à 12 heures. Les données des essais cliniques montrent que le modafinil réduit la somnolence diurne chez les personnes atteintes de ce trouble et améliore également leur capacité à effectuer des activités de routine telles que la lecture, la conduite et le travail. De faibles doses augmentent généralement l'éveil, tandis que des doses élevées augmentent la somnolence. D'autres effets de la drogue comprennent une plus grande volonté d'accomplir des tâches, une capacité à maintenir la concentration et le traitement cognitif, une mémoire améliorée, un sens de l'acuité mentale, une capacité à apprendre et à retenir de nouvelles informations et une capacité à retenir les détails d'une tâche complexe. Les récepteurs de la dopamine jouent également un rôle dans l'intégration des signaux hormonaux, ce qui pourrait expliquer pourquoi le modafinil augmente les niveaux de testostérone et de cortisol. Le but du modafinil a été étiqueté comme "amélioration neurologique" et "amélioration cognitive", généralement utilisé pour décrire les médicaments améliorant la performance. Le modafinil n'est pas approuvé pour cette utilisation. La demi-vie d'élimination est de 16 à 20 heures. Comme les autres stimulants, il a une demi-vie de 5 à 7 heures.
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