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Le modafinil est un stimulant du systГЁme nerveux central utilisГ© pour traiter la somnolence due Г la narcolepsie, les troubles du sommeil liГ©s au travail postГ© et l'apnГ©e obstructive du sommeil. Des doses supГ©rieures Г 400 mg ont Г©tГ© utilisГ©es avec le mГЄme niveau d'efficacitГ©. Le modafinil semble Г©galement affecter la sГ©rotonine, la dopamine et l'histamine sur ses sites d'action, ce qui peut contribuer Г ses effets d'amГ©lioration cognitive. La recherche indique que le modafinil augmente l'Г©veil, rГ©duit la somnolence diurne et augmente la mГ©moire de travail. La biodisponibilitГ© du modafinil est d'environ 85 %. Pour les troubles du sommeil liГ©s au travail postГ©, 200 mg de modafinil sont prescrits deux fois par jour. Stimulant Intellectuel Sans Ordonnance Le modafinil est disponible sous forme de comprimГ©s de 100 mg, 200 mg et 400 mg, et il peut Г©galement ГЄtre pris en une seule dose quotidienne de 200 mg. Une revue Cochrane de 2017 a conclu que le modafinil Г©tait efficace pour le traitement de la somnolence excessive chez les adultes atteints de narcolepsie et a effectivement inversГ© les troubles cognitifs du trouble. Le modafinil est un mГ©tabolite actif du mГ©dicament Provigil. [1] Il diffГЁre des Г©nantiomГЁres du modafinil par le fait que l'isomГЁre (S) du cycle tГ©trahydrobenzazГ©pine est substituГ© par un atome de chlore en position 5 et un groupe mГ©thyle en position 7. Dans la voie mГ©solimbique, le modafinil augmente les niveaux de dopamine dans le noyau accumbens, ainsi que dans l'amygdale, ce qui aide Г rГ©guler les Г©motions et l'excitation physiologique. En 1999, une version gГ©nГ©rique a Г©tГ© approuvГ©e aux Г‰tats-Unis. Le modafinil pourrait ГЄtre utile dans les troubles caractГ©risГ©s par une somnolence excessive comme la narcolepsie, les troubles du travail postГ© et l'apnГ©e obstructive du sommeil. Le modafinil est dГ©composГ© par la plasma-carbamoyl-phosphate synthГ©tase en son principal mГ©tabolite, le N-dГ©sГ©thyl modafinil. Pour ce faire, il augmente le nombre de neurotransmetteurs appelГ©s dopamine et noradrГ©naline qui vous aident Г rester Г©veillГ©. Le modafinil est utilisГ© pour la somnolence causГ©e par la narcolepsie, les troubles du sommeil liГ©s au travail postГ© et l'apnГ©e obstructive du sommeil. Le mГ©dicament augmente l'Г©veil et, Г fortes doses, amГ©liore Г©galement la motivation au travail et la mГ©moire Г court terme. Le modafinil n'est pas recommandГ© pour un usage pГ©diatrique. Le modafinil, Г©galement connu sous le nom de Provigil, est un mГ©dicament stimulant et favorisant l'Г©veil.
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Stimulant Intellectuel Sans Ordonnance - by Modafinil 200 - 01-11-2023, 07:09 AM
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