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#7
Dans une molГ©cule, le modafinil contient une structure chimique similaire Г  l'amphГ©tamine et au mГ©thylphГ©nidate et appartient Г  une classe de mГ©thylphГ©nidates. Г‰tant donnГ© que le modafinil est mГ©tabolisГ© par la mГЄme enzyme qui dГ©compose de nombreux mГ©dicaments couramment utilisГ©s, tels que l'alcool et la cafГ©ine, il peut interagir avec l'action de ces mГ©dicaments. Le modafinil semble Г©galement inhiber plusieurs enzymes impliquГ©es dans la recapture de la dopamine, de la noradrГ©naline et de la sГ©rotonine. Le modafinil est un agoniste dopaminergique faible et un agoniste complet des rГ©cepteurs dopaminergiques D2 et D3, mais aucun agoniste des rГ©cepteurs dopaminergiques D1 et D4. Il est donc recommandГ© aux patients de ne pas utiliser d'autres stimulants tels que la cafГ©ine, l'alcool ou la nicotine pendant qu'ils sont sous modafinil. Le modafinil n'est pas considГ©rГ© comme sГ»r pendant la grossesse ou l'allaitement. Le modafinil est un stimulant relativement puissant. La somnolence due Г  la narcolepsie survient pendant la journГ©e, tandis que la somnolence des deux autres troubles survient la nuit. Une arythmie est une condition dans laquelle le systГЁme Г©lectrique du cЕ“ur ne fonctionne pas correctement. Le modafinil a Г©tГ© utilisГ© comme stimulant pour rester Г©veillГ© au travail. Les formes en vente libre sont prises jusqu'Г  quatre fois par jour, une dose initiale Г©tant prise le matin et des doses supplГ©mentaires Г  intervalles rГ©guliers tout au long de la journГ©e. nootropique pharmacie Le modafinil est un mГ©dicament d'ordonnance qui n'offre pas les mГЄmes avantages s'il est pris Г  des moments similaires de la journГ©e. Le modafinil inhibe la catalase, une enzyme dans le sang qui dГ©truit les radicaux d'oxygГЁne. Il n'est pas recommandГ© chez les personnes souffrant d'arythmie, d'hypertension artГ©rielle, d'hypertrophie ventriculaire gauche importante ou de dГ©pression. Le modafinil a Г©tГ© utilisГ© hors AMM pour le traitement de la somnolence excessive chez les enfants et les adultes atteints de narcolepsie, pour pouvoir travailler de plus longues heures sans ГЄtre fatiguГ© et pour plusieurs autres problГЁmes, notamment aider les gens Г  se concentrer, Г  amГ©liorer leur humeur et leur Г©nergie et Г  stimuler leur poids. Parmi les effets secondaires les plus courants figurent la somnolence, les maux de tГЄte et les nausГ©es. L'Г©quivalent gГ©nГ©rique de Provigil est Provigil 200 mg. lactose, cellulose microcristalline, mannitol et stГ©arate de magnГ©sium. Il est disponible sous forme de caplet qui peut ГЄtre avalГ© avec de l'eau ; une tablette; ou sous une forme Г  libГ©ration modifiГ©e (Provigil SR) qui peut ГЄtre prise une fois par jour. Les effets secondaires du modafinil comprennent des maux de tГЄte, des troubles du sommeil et des nausГ©es. De plus, le modafinil semble ГЄtre responsable de la restauration des neuropeptides orexine. Bien que le mГ©canisme d'action prГ©cis soit inconnu, il semble agir au niveau des ganglions de la base, des centres mГ©solimbiques et cГ©rГ©belleux du cerveau. Il est vendu sous forme de comprimГ© et est commercialisГ© aux Г‰tats-Unis sous le nom de Concerta par Sunovion Pharmaceuticals Inc.

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#8
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#9
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#10
Jan Webster from Grand Prairie was looking for topics for a research proposal

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