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modafinil

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modafinil
#1
Les effets secondaires plus graves peuvent inclure la dГ©pendance physique, l'anxiГ©tГ©, la dГ©pression, les troubles de l'humeur et les attaques de panique. Il a la formule molГ©culaire C8H11N3O2S2 et est un ester sulfamate de propyl-para-hydroxyamphГ©tamine (PAH). Le modafinil rГ©duit le niveau de stimulation du systГЁme nerveux et augmente l'activitГ© du systГЁme nerveux. La Cmax est atteinte lorsque le modafinil est pris le matin. Le mГ©dicament est vendu sous diverses marques sous forme de comprimГ©s et de gГ©lules Г  libГ©ration immГ©diate (IR) et Г  libГ©ration prolongГ©e (XR). Cela agit principalement en stimulant la partie "noradrГ©nergique" du cortex cГ©rГ©bral, bien qu'il soit Г©galement associГ© Г  l'augmentation de la libГ©ration de noradrГ©naline. Certains citent jusqu'Г  200 mg comme acceptable pour la cognition, tandis que des rapports plus rГ©cents suggГЁrent 300 mg comme dose optimale recommandГ©e pour les humains. Le modafinil est une substance contrГґlГ©e de classe C aux Г‰tats-Unis. Comme les amphГ©tamines, le modafinil est un stimulant "non benzodiazГ©pine". Le modafinil a une demi-vie d'environ six heures, bien qu'il soit mГ©tabolisГ© beaucoup plus lentement que les autres stimulants. Le nom В« Modafinil В» vient des premiГЁres lettres de Michel Jouvet et des Laboratoires Lafon, la sociГ©tГ© qui a inventГ© le composГ©. modafinil Le modafinil a Г©tГ© commercialisГ© comme un "mГ©dicament intelligent" et utilisГ© comme aide pour surmonter la dГ©pression. On pense que le modafinil est efficace dans la dГ©pression, car il Г©lГЁve les niveaux de dopamine et Г©ventuellement d'acГ©tylcholine. Il est considГ©rГ© comme environ 10 fois plus puissant que l'amphГ©tamine. Il a Г©tГ© dГ©montrГ© que le modafinil augmente le risque de crises d'Г©pilepsie lorsqu'il est associГ© Г  d'autres mГ©dicaments anticonvulsivants. En 2017, c'Г©tait le 7e mГ©dicament sur ordonnance le plus populaire aux Г‰tats-Unis. La cafГ©ine a largement remplacГ© le modafinil aux Г‰tats-Unis. Le modafinil est utilisГ© dans le traitement de la somnolence excessive due Г  la narcolepsie et aux troubles du travail postГ©. L'effet de ces doses est beaucoup plus important que l'effet de doses plus faibles, et ils peuvent provoquer des effets secondaires considГ©rables s'ils sont consommГ©s en plus grande quantitГ©. Il y a des suggestions qu'il peut ГЄtre utile comme traitement pour divers troubles neurologiques. Le modafinil (Modalert) est indiquГ© pour le traitement temporaire de la somnolence diurne excessive associГ©e au syndrome d'apnГ©e du sommeil, de la somnolence due Г  la narcolepsie et des troubles du sommeil liГ©s au travail postГ©. Le modafinil semble Г©galement ГЄtre un faible antagoniste des rГ©cepteurs adrГ©nergiques alpha-1. Le modafinil et d'autres stimulants peuvent provoquer de graves rГ©actions cardiovasculaires, psychiatriques et dermatologiques.

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