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Le modafinil inhibe la dГ©gradation enzymatique de l'ACh, favorisant des niveaux plus Г©levГ©s dans le cerveau. La demi-vie du modafinil est plus longue que celle des amphГ©tamines, ce qui lui permet de rester plus longtemps dans le cerveau. Le 22 novembre 2016, le commissaire de la FDA a annoncГ© que l'agence chercherait Г mettre fin Г sa dГ©signation du modafinil comme mГ©dicament d'ordonnance parce qu'elle ne le considГЁre plus comme sГ»r et efficace, et que toutes les allГ©gations actuelles pour le modafinil sont "fausses et sans fondement. La posologie est basГ©e sur la rГ©ponse du patient. Modafinil fonctionne plus efficacement Г des doses plus Г©levГ©es. Le modafinil affecte le SNC en agissant sur des sites du cerveau qui contrГґlent l'Г©veil et le sommeil. Le but principal du modafinil dans la vie est d'aider les gens Г rester Г©veillГ©s. Le modafinil aurait une demi-vie d'environ 9 Г 11 h. Contrairement Г d'autres stimulants, tels que le modafinil et le mГ©thylphГ©nidate, le modafinil ne semble pas avoir un potentiel d'abus Г©levГ© et peut ГЄtre utilisГ© sans ordonnance. Le modafinil est disponible en tant que mГ©dicament gГ©nГ©rique, avec le nom de marque Provigil vendu aux Г‰tats-Unis, au Royaume-Uni et dans d'autres pays. Le modafinil est associГ© Г un risque lГ©gГЁrement accru de dГ©pression chez certaines personnes. La noradrГ©naline est libГ©rГ©e dans le cerveau lorsqu'une personne est exposГ©e au stress ou s'engage dans certaines tГўches telles que le travail, l'exercice ou l'apprentissage. Cette Г©tude a rГ©vГ©lГ© que le modafinil augmentait le nombre de cellules dans le cerveau qui expriment c-fos, une protГ©ine qui active d'autres gГЁnes qui contribuent Г l'Г©veil et qui est Г©galement produite lors de la mort des cellules cГ©rГ©brales. Nootropique En Pharmacie Le modafinil peut Г©galement avoir des effets additifs avec d'autres stimulants du SNC tels que l'amphГ©tamine et le mГ©thylphГ©nidate. Il est Г©galement utilisГ© pour traiter la somnolence excessive causГ©e par le travail postГ© ainsi que l'apnГ©e obstructive du sommeil. Si ces rГ©actions surviennent, contactez d'abord votre mГ©decin prescripteur. Cette recherche sur le modafinil est toujours activement Г©tudiГ©e. Non seulement cela augmente la vigilance, mais cela peut Г©galement amГ©liorer l'humeur et la motivation, permettant au patient de travailler plus longtemps, souvent Г des niveaux de productivitГ© auxquels il ne pourrait pas travailler s'il Г©tait bien reposГ©. Des essais en double aveugle sont utilisГ©s dans lesquels la personne qui prend le mГ©dicament et les personnes qui administrent les tests ne savent pas dans quel groupe se trouvent les sujets. Il est Г©galement utilisГ© dans les situations de perte de sommeil rГ©currente qui surviennent pendant le travail postГ©. Il a Г©tГ© mis Г la disposition du public pour la premiГЁre fois aux Г‰tats-Unis en 1998. Le modafinil est un stimulant du systГЁme nerveux central (SNC) qui agit en augmentant l'Г©veil et la capacitГ© Г effectuer des tГўches. Pour Г©viter l'induction du sommeil Г partir d'une dose de 300 mg, trois Г quatre jours doivent ГЄtre autorisГ©s entre les doses. Provigil est actuellement rГ©pertoriГ© par la Food and Drug Administration (FDA) des Г‰tats-Unis en tant que mГ©dicament sur ordonnance avec un certain nombre d'applications mГ©dicales. La Food and Drug Administration (FDA) des Г‰tats-Unis a approuvГ© le Modafinil aux Г‰tats-Unis pour le traitement de la somnolence excessive associГ©e Г des affections telles que les troubles du sommeil liГ©s au travail postГ©, la narcolepsie et l'apnГ©e obstructive du sommeil. En tant que stimulant du SNC, le modafinil agit en amГ©liorant la neurotransmission dans le cerveau et le systГЁme nerveux. La stimulation de ces neurones peut provoquer plusieurs types d'effets sur les nerfs, les muscles et les glandes.
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