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06-23-2023, 10:46 PM
(This post was last modified: 06-23-2023, 10:47 PM by Le Modafinil .)
Le modafinil peut Г©galement empГЄcher la dГ©gradation d'un autre neurotransmetteur, la dopamine. Le modafinil met un peu plus de temps Г se dissoudre que les autres mГ©dicaments. Le modafinil est un inhibiteur spГ©cifique de l'enzyme hydrolase des amides d'acides gras (FAAH), qui dГ©grade les endocannabinoГЇdes (anandamide et 2-arachidonoylglycГ©rol), les principaux neurotransmetteurs inhibiteurs naturels dans le cerveau. Cependant, en ligne, vous pouvez obtenir du Modafinil dans une large gamme de dosages diffГ©rents et mГЄme Г des doses personnalisГ©es. Le modafinil est un mГ©dicament stimulant qui augmente le flux sanguin vers certaines parties du cerveau, notamment l'hypothalamus et le locus coeruleus. Il doit ГЄtre conservГ© au rГ©frigГ©rateur ou dans un endroit ombragГ© pour Г©viter toute exposition Г la lumiГЁre directe, ce qui peut rendre le mГ©dicament instable. vigilance. Il a Г©tГ© utilisГ© comme В«mГ©dicament de l'Г©veilВ», terme juridique dГ©signant une substance pharmaceutique commercialisГ©e pour sa capacitГ© Г augmenter la vigilance. Le modafinil a Г©tГ© dГ©veloppГ© dans les annГ©es 1970 par le chimiste Pierre Modave, puis dГ©veloppГ© par Michel Jouvet Г l'Institut Caven-de-Boulogne en France, oГ№ il a Г©tГ© utilisГ© pour la premiГЁre fois chez les personnes atteintes de narcolepsie. Le modafinil est un stimulant dГ©veloppГ© en France par le Dr Michel Jouvet dans le but de traiter la narcolepsie.
modiodal drogue Il peut provoquer une lГ©gГЁre augmentation de la pression artГ©rielle, de sorte que les personnes souffrant d'hypertension artГ©rielle doivent ГЄtre particuliГЁrement prudentes lorsqu'elles prennent le mГ©dicament. L'amГ©lioration de ce mГ©canisme peut ГЄtre la raison de l'utilisation rГ©ussie du modafinil dans le travail postГ©. Dans l'autre Г©tude, ils ont Г©tГ© augmentГ©s de 15 % dans les noyaux caudГ©s et de 27 % dans le cortex prГ©frontal, un changement positif associГ© Г une augmentation de l'Г©veil. Une analyse chimique du comprimГ© de modafinil montre qu'il contient 185 mg de modafinil, 4,85 mg de dextroamphГ©tamine, 17,87 mg de cafГ©ine et 8,07 mg de paracГ©tamol. Le modafinil est un agoniste des rГ©cepteurs de la dopamine censГ© favoriser l'Г©veil et le maintien de l'Г©veil. Le modafinil agit sur les rГ©cepteurs de la dopamine dans les lobes frontaux du cerveau et agit en rendant la dopamine plus disponible et accessible au cerveau. D'autres effets secondaires incluent des troubles du sommeil, une bouche sГЁche, un nez gonflГ©, une dГ©shydratation, une diarrhГ©e, une diminution de l'appГ©tit, des nausГ©es, des vomissements, de la constipation, de l'acnГ© et des dГ©mangeaisons. Le modafinil est gГ©nГ©ralement bien tolГ©rГ©, avec des effets secondaires possibles, notamment des maux de tГЄte, des troubles du sommeil et des nausГ©es. Bien que le modafinil ait Г©tГ© initialement dГ©veloppГ© comme aide au sommeil, il est maintenant utilisГ© principalement pour traiter les troubles du sommeil liГ©s au travail postГ© et la somnolence due Г la narcolepsie. Comme avec tous les mГ©dicaments, des complications peuvent survenir. Le modafinil a Г©tГ© approuvГ© comme traitement de la somnolence due Г la narcolepsie en 1995 par la Food and Drug Administration (FDA) des Г‰tats-Unis. Le modafinil est un mГ©dicament stimulant qui favorise l'Г©veil via la stimulation du systГЁme nerveux central (SNC). On pense qu'il modifie les niveaux d'adГ©nosine monophosphate cyclique (AMPc), ce qui affecte la signalisation de l'Г©veil.
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ConsidГ©rГ© par certains comme une "pilule intelligente", le modafinil a Г©tГ© utilisГ© pour amГ©liorer l'Г©veil dans un certain nombre d'industries, afin d'amГ©liorer la productivitГ© des travailleurs postГ©s, tels que les enseignants et les agents de bord. Le modafinil peut Г©galement ГЄtre pris comme supplГ©ment Г base de plantes, qui n'est pas rГ©glementГ© et peut ГЄtre dangereux. Le modafinil augmente le flux sanguin et on pense Г©galement qu'il traverse la barriГЁre hГ©mato-encГ©phalique. Le modafinil n'est pas un remГЁde pour ces troubles. Il n'a pas Г©tГ© dГ©terminГ© si Modafinil est sГ»r Г utiliser pendant la grossesse. La plupart des gens commencent Г remarquer des effets dans les 15 minutes. Le chlorhydrate est une poudre cristalline blanche lГ©gГЁrement hygroscopique qui est librement soluble dans l'eau. Alors que les amphГ©tamines sont des stimulants, les cyclopyrrolones sont des dГ©presseurs du SNC (contrairement aux barbituriques par exemple). Il a Г©tГ© utilisГ© comme mГ©dicament pour les personnes sГ©ropositives afin de rГ©duire le risque de dГ©velopper le complexe de dГ©mence du SIDA. La libГ©ration de cette substance entraГ®ne une sensation d'Г©veil. Le modafinil n'est pas recommandГ© aux personnes souffrant de maladies cardiovasculaires importantes, d'antГ©cГ©dents de convulsions, d'hypertension modГ©rГ©e ou sГ©vГЁre ou de rythmes cardiaques anormaux. Il n'est pas recommandГ© chez les personnes souffrant d'arythmie, d'hypertension artГ©rielle importante ou d'hypertrophie ventriculaire gauche.
modiodal drogue Cependant, il n'est pas recommandГ© par la FDA pour une utilisation comme activateur cognitif. L'efficacitГ© du modafinil pour ceux qui ont seulement besoin de maintenir leur vigilance a Г©tГ© Г©valuГ©e dans un essai randomisГ© en simple aveugle contre placebo. Le modafinil aide le cerveau Г rester Г©veillГ© et alerte, en particulier pendant la partie Г©veillГ©e de la nuit. Il est Г©galement important de boire beaucoup d'eau pendant la journГ©e. Jusqu'Г prГ©sent, cependant, les essais cliniques sur le modafinil n'ont pas dГ©montrГ© de maniГЁre concluante son efficacitГ© Г court ou Г long terme. Shawn Christopher, PharmD, CDE, du Public Citizen Drug Information Service, a passГ© en revue plus de 50 Г©tudes sur le modafinil. Les comprimГ©s de 500 mg peuvent ГЄtre coupГ©s en deux et avalГ©s. Comme d'autres stimulants sur ordonnance, le modafinil n'est pas recommandГ© pour le traitement de l'obГ©sitГ© ou le traitement du trouble dГ©ficitaire de l'attention avec hyperactivitГ© chez les enfants. Le modafinil est un stimulant irrГ©versible Г action rapide. Ceci est soutenu par son affinitГ© pour les rГ©cepteurs dopaminergiques D1, D2, D3 et D4. En plus de son action stimulante, il agit comme un inhibiteur rГ©versible de l'enzyme qui dГ©compose la sГ©rotonine. La substance est chimiquement identique aux stimulants mГ©thylphГ©nidate et amphГ©tamine.
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