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Le mГ©decin connaГ®tra la dose correcte de modafinil pour chaque patient. Selon le fabricant, des doses plus Г©levГ©es peuvent produire de la somnolence chez ceux qui essaient de s'y habituer. Le modafinil est connu pour interagir avec le mГ©thylphГ©nidate en ce sens qu'il peut augmenter les niveaux de mГ©thylphГ©nidate dans le corps. Il est lentement Г©liminГ© de l'organisme principalement par l'urine et la bile. Le modafinil est un mГ©lange racГ©mique de modafinil d- et l-modafinil. Comme l'amphГ©tamine, le modafinil agit Г©galement sur le transporteur de la dopamine dans le cerveau, augmentant la disponibilitГ© de la dopamine au niveau de ses rГ©cepteurs. Le modafinil est considГ©rГ© comme moins efficace contre l'insomnie que les autres somnifГЁres en raison de ses effets sur le neurotransmetteur dopaminergique dans le cerveau. Le modafinil n'est pas une substance contrГґlГ©e aux Г‰tats-Unis et est disponible sans ordonnance. Il se lie au transporteur de la dopamine et produit des effets opposГ©s aux amphГ©tamines et empГЄche la recapture de la dopamine. Certains suggГЁrent que le modafinil soit utilisГ© comme complГ©ment alimentaire pour l'amГ©lioration cognitive. Un mГ©dicament apparentГ©, l'armodafinil, est utilisГ© pour traiter la narcolepsie. Le modafinil est gГ©nГ©ralement considГ©rГ© comme sГ»r pour ceux qui ont eu un accident vasculaire cГ©rГ©bral ou d'autres conditions mГ©dicales qui augmentent le risque de maladie cardiaque, bien qu'il puisse ГЄtre dangereux pour les personnes Г risque de convulsions. C'est pourquoi les somnifГЁres fonctionnent Г©galement, mais ils bloquent Г la fois la dopamine et les neurotransmetteurs noradrГ©naline et facilitent ainsi l'endormissement. On pense que le modafinil favorise l'Г©veil en augmentant le nombre de sites rГ©cepteurs disponibles pour la dopamine (un neurotransmetteur dans le cerveau) dans le cerveau. Cette amГ©lioration peut se produire indГ©pendamment du fait que l'utilisateur soit obligГ© de rester Г©veillГ© ou qu'il s'autorise Г faire une sieste. Acheter Modafinil En Luxembourg Dans ce cadre, il est pris principalement le soir pour augmenter la latence du sommeil et peut ГЄtre pris pendant plusieurs semaines avant de commencer Г montrer des rГ©sultats. Enfin, on pense que le modafinil amГ©liore la vigilance en inhibant les rГ©cepteurs de l'adГ©nosine inhibant le sommeil dans le cervelet. Le modafinil est Г©galement utilisГ© pour traiter le trouble du rythme circadien du sommeil, une condition qui survient gГ©nГ©ralement chez les travailleurs postГ©s oГ№ il y a une perturbation du rythme circadien ou du rythme naturel du sommeil. Certains mГ©dicaments interagissent avec le modafinil, mais on ne sait pas si ces interactions sont nocives. Le modafinil est Г©galement disponible sous forme de libГ©ration prolongГ©e, qui dure plus longtemps et libГЁre le mГ©dicament tout au long de la nuit. Une utilisation importante du modafinil est d'amГ©liorer la vigilance chez les personnes souffrant de troubles du sommeil liГ©s au travail postГ©. Un apport Г©levГ© en cafГ©ine est recommandГ© lors de l'utilisation du modafinil. Cela augmente la quantitГ© de sГ©rotonine disponible pour le cerveau. Il n'est pas approuvГ© pour une utilisation Г cette fin chez les enfants, mais certains mГ©decins le prescrivent pour des problГЁmes de sommeil mineurs chez les enfants et les adolescents et chez les Г©tudiants. Il a une formule structurelle, C15H15NO2, similaire Г celle de l'amphГ©tamine, mais il diffГЁre en ce qu'il possГЁde un pont carbone plutГґt qu'un pont azote entre les cycles n-mГ©thyle et morpholine. Si l'effet dГ©sirГ© n'est pas atteint, la dose doit ГЄtre diminuГ©e de moitiГ©. La majeure partie du modafinil est ensuite mГ©tabolisГ©e en phГ©nylacГ©tone par le CYP3A4. L'efficacitГ© du modafinil pour ceux qui ont seulement besoin de maintenir leur vigilance a Г©tГ© Г©valuГ©e dans un essai randomisГ© en simple aveugle contre placebo.
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