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06-23-2023, 03:54 PM
(This post was last modified: 06-23-2023, 03:55 PM by Le Modafinil .)
Il est actuellement disponible sous une forme générique auprès de plusieurs fabricants. Le modafinil est disponible dans la gamme de doses de 100 à 200 mg. Il peut avoir des effets négatifs sur les paramètres cardiovasculaires et la tension artérielle. Il existe également des effets secondaires peu fréquents et rares qui peuvent survenir. Internet. Le modafinil a été développé dans les années 1970 par le neuroscientifique français Michel Jouvet et les laboratoires Lafon. Les stimulants de type amphétamine sont classés dans la catégorie des produits de type amphétamine. Le modafinil agit en inhibant la dégradation du neurotransmetteur acétylcholine, augmentant le niveau de ce neurotransmetteur dans la synapse, la connexion entre les deux cellules. Pour les travailleurs postés prenant plusieurs doses tout au long de la journée, il est recommandé de commencer par 100 mg pour la première dose, puis d'augmenter de 100 mg toutes les deux à trois heures. Dans la narcolepsie, les neurones qui contrôlent le système moteur dans le cerveau sont très sensibles à la stimulation. Le médicament semble améliorer l'attention et la mémoire de travail dans les tâches cognitives en augmentant les niveaux de dopamine, à la fois au centre du cerveau et en périphérie dans la circulation sanguine. Des études chez le rat montrent que les niveaux de norépinéphrine dans le cerveau culminent dans les 5 à 15 minutes suivant l'administration de modafinil et que les niveaux de dopamine augmentent dans les 30 minutes. Le modafinil est fabriqué par Covidien (WakeMed Pharmacy, Inc. Son nom chimique est l'acide N-benzylpipéridine-2-carboxylique et c'est une amphétamine substituée.
modiodal sans ordonnance Mais il est connu pour fonctionner comme un stimulant pour amГ©liorer la conscience et l'Г©nergie, et est parfois utilisГ© pour traiter le TDAH et l'incapacitГ© Г se concentrer causГ©e par une grave privation de sommeil. Le modafinil a un degrГ© Г©levГ© de sГ©lectivitГ© pour les transporteurs de recapture de la dopamine par rapport aux transporteurs de recapture de la sГ©rotonine. La premiГЁre phase a Г©tГ© le dГ©veloppement de la recherche chez les animaux. Le modafinil est utilisГ© pour traiter la somnolence diurne excessive rГ©sultant de la narcolepsie ou des troubles du sommeil liГ©s au travail postГ© et pour traiter l'apnГ©e obstructive du sommeil. Il a un profil pharmacologique unique, car c'est un antagoniste compГ©titif des rГ©cepteurs DA (rГ©cepteur D2/D2). Le modafinil est un stimulant du systГЁme nerveux central (SNC) et est classГ© comme drogue dans la classe des amphГ©tamines. Il n'est pas recommandГ© aux personnes qui ne tolГЁrent pas le mГ©dicament car il peut provoquer des effets secondaires et aggraver les symptГґmes. Le modafinil est un inhibiteur sГ©lectif de la recapture de l'histamine. Les effets secondaires rares et graves comprennent des convulsions, des rГ©actions allergiques telles que l'anaphylaxie et le syndrome de Stevens-Johnson, des hallucinations et des problГЁmes de peau ou d'autres organes. Les effets indГ©sirables qui peuvent survenir comprennent, mais sans s'y limiter, des maux de tГЄte, des nausГ©es et des Г©ruptions cutanГ©es. En raison de l'effet paradoxal du modafinil sur le cycle du sommeil, un effet secondaire courant dans les essais sur les animaux et les humains est l'agitation.
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Il agit en stimulant le SNC, en particulier le systГЁme orexine, qui est important dans le cycle veille/sommeil. En 1998, il a Г©tГ© approuvГ© aux Г‰tats-Unis comme traitement des troubles du sommeil liГ©s au travail postГ©, et en France, il a Г©galement Г©tГ© utilisГ© pour traiter la toxicomanie. Il est Г©galement approuvГ© chez les adultes souffrant de somnolence excessive due Г une apnГ©e obstructive du sommeil, et chez les adultes souffrant d'un sommeil insuffisant dГ» au travail postГ©, en raison du manque d'alternatives non mГ©dicamenteuses efficaces dans ces populations. Cette quantitГ© Г©quivaut gГ©nГ©ralement Г 100 mg de cafГ©ine, cependant, la prise de Modafinil de cette maniГЁre signifie que le corps ne mГ©tabolise pas Г©galement la cafГ©ine, ce qui peut augmenter le risque d'effets secondaires. L'effet prolongГ© de la dopamine dans le striatum augmente alors la vigilance et l'Г©veil de la personne prenant du modafinil. Le dГ©but d'action du modafinil se situe dans les 30 minutes et les effets durent jusqu'Г 12 heures. Il est disponible dans les dosages de 300 mg et 400 mg dans les pharmacies uniquement sur ordonnance. Le Modafinil a Г©tГ© dГ©veloppГ© dans les annГ©es 1970 par le Dr Michel Jouvet et les Laboratoires Lafon en France, Г partir de recherches menГ©es en collaboration avec le CNRS, Centre National de la Recherche Scientifique. Le modafinil est plus sГ©lectif pour le systГЁme nerveux central, et moins pour le systГЁme endocrinien, que la cafГ©ine. Il est mГ©tabolisГ© dans le foie. Il n'a pas Г©tГ© prouvГ© que le modafinil fonctionne pour le traitement du TDAH. Bien qu'une dose unique chez des personnes en bonne santГ© ne semble pas altГ©rer la fonction cognitive, elle peut altГ©rer les performances psychomotrices Г des doses de 200 Г 400 mg chez les personnes ГўgГ©es et les personnes souffrant d'apnГ©e du sommeil prГ©existante.
modiodal sans ordonnance Le nom chimique du modafinil est 2-[(dipropylamino)mГ©thyl]-1-benzothiophГЁne. Le modafinil peut ГЄtre utilisГ© pour traiter un certain nombre de troubles du sommeil, notamment la narcolepsie, l'apnГ©e du sommeil, les troubles du sommeil liГ©s au travail postГ© et autres. Les quantitГ©s quotidiennes prises peuvent devoir ГЄtre augmentГ©es. Plusieurs lignes directrices recommandent son utilisation pour les personnes souffrant d'apnГ©e du sommeil. Outre le modafinil, les autres agents nootropes notables de l'industrie pharmaceutique comprennent le piracГ©tam et l'aniracГ©tam, des nootropes qui sont devenus cГ©lГЁbres parmi les accros de la santГ© et de la forme physique en raison de leur notoriГ©tГ© et de leur potentiel de stimulation du cerveau. Le modafinil peut ГЄtre pris Г jeun, ou avec un repas ou une boisson. Le modafinil augmente la vigilance en amГ©liorant le cycle veille-sommeil pour rester alerte. Le modafinil peut avoir une comprГ©hension claire des interactions mГ©dicamenteuses. Le modafinil est un stimulant prescrit pour le traitement d'entretien de la narcolepsie, qui est un trouble du sommeil qui provoque une somnolence excessive et des troubles du sommeil. Il a Г©tГ© initialement approuvГ© pour le traitement de la narcolepsie par l'Agence nationale de sГ©curitГ© sanitaire des aliments (Agence Nationale de SГ©curitГ© Sanitaire de l'Alimentation, de l'Environnement et du Travail, ou ANSM) en 1994. On ne pense pas que cette action soit due Г l'interaction spГ©cifique du modafinil avec des cibles spГ©cifiques dans le cerveau, mais plutГґt Г un changement gГ©nГ©ral de l'Г©quilibre excitation/inhibition du cerveau, qui Г son tour affecte les temps d'attention et de rГ©action. Il peut provoquer une mort subite chez les personnes souffrant de maladies cardiaques. La formule chimique du modafinil est C14H16N2O2S. Le modafinil peut Г©galement aider Г soulager les symptГґmes de la dГ©pression bipolaire et unipolaire.
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