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Ceux qui sont diabГ©tiques peuvent le prendre avec un repas. MГ©canisme d'action : Un analogue de la dopamine non stimulant qui agit sur le systГЁme noradrГ©nergique du SNC. Bien qu'initialement dГ©veloppГ© comme mГ©dicament psychiatrique, au cours de la derniГЁre dГ©cennie, il a Г©tГ© plus largement utilisГ© comme mГ©dicament amГ©liorant la cognition pour amГ©liorer l'Г©veil. Le mГ©dicament augmente l'Г©veil et amГ©liore l'humeur et le fonctionnement cognitif chez les personnes souffrant d'Г©pisodes de sommeil prolongГ©s dus Г des troubles tels que la narcolepsie et les troubles du travail postГ©. Il est important de tenir compte de chaque patient et de la condition mГ©dicale spГ©cifique traitГ©e avant d'utiliser ce mГ©dicament. Environ 50 % des personnes ayant une affinitГ© connue pour le modafinil sont porteuses du variant CYP2D6. Le modafinil est une phГ©nГ©thylamine synthГ©tique, un stimulant et un coupe-faim. Le modafinil augmente le niveau des neurotransmetteurs dopamine, noradrГ©naline et sГ©rotonine dans le cerveau. Au contraire, le modafinil agit pour favoriser l'Г©veil. La quantitГ© d'acГ©tylcholine libГ©rГ©e est augmentГ©e en consГ©quence, ce qui entraГ®ne une augmentation des niveaux de vigilance et d'Г©veil.
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