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Le principal ingrédient actif du médicament est le modafinil. Le modafinil est disponible en tant que médicament générique. Le modafinil est un stimulant du système nerveux central qui aide les gens à rester éveillés pendant leur sommeil. Il en résulte une activité supplémentaire de NE dans le système nerveux central. Il augmente l'éveil et améliore l'attention, sans provoquer de changements d'humeur ni d'effets secondaires, et on pense qu'il agit par l'inhibition sélective de la recapture de la mélatonine et de la sérotonine. Commander Modafinil En Ligne Cependant, les recherches sont insuffisantes pour déterminer si les avantages du médicament l'emportent sur les risques et les coûts. Le modafinil a été développé à l'origine pour traiter un trouble connexe, le trouble du sommeil lié au travail posté, dans lequel ce trouble de la phase de sommeil circadien est associé à une somnolence pendant la journée due au travail de nuit. L'effet secondaire le plus courant est la difficulté à dormir. Au Royaume-Uni, il s'agit d'un médicament délivré uniquement sur ordonnance. Il est également utilisé hors AMM comme stimulant cognitif pour prévenir la somnolence chez les patients souffrant de troubles du sommeil liés au travail posté et d'apnée obstructive du sommeil. Le modafinil a été développé par le neuroscientifique français Michel Jouvet et les laboratoires Lafon pour traiter les symptômes de la narcolepsie. Les effets secondaires courants du modafinil comprennent les maux de tête, la bouche sèche, les nausées et les troubles du sommeil. Le médicament est efficace dans les deux conditions, mais fonctionne mieux dans les troubles du sommeil liés au travail posté. De plus, dormir dans un endroit dangereux, comme conduire ou faire fonctionner des machines, est plus susceptible de provoquer des accidents mortels. Il a été démontré que le modafinil augmente l'éveil en améliorant plusieurs composants du sommeil, principalement en augmentant le sommeil à ondes lentes et en diminuant le sommeil paradoxal.

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