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06-25-2023, 11:30 AM
(This post was last modified: 06-25-2023, 11:30 AM by Le Modafinil .)
Le modafinil n'a pas Г©tГ© approuvГ© pour une utilisation dans le traitement de la schizophrГ©nie. Il est produit sous forme d'Г©nantiomГЁre R-(-) du 2-(benzhydrylsulfinyl)acГ©tamide. Plus d'informations peuvent ГЄtre trouvГ©es dans les sources Г©numГ©rГ©es ci-dessous. Le modafinil est un mГ©dicament utilisГ© pour traiter la somnolence excessive et aider les gens Г s'endormir. п»їLe modafinil se prГ©sente sous forme de comprimГ©s, de suspension et de sirop. La dose de modafinil est gГ©nГ©ralement comprise entre 100 et 200 mg par jour. Il agit principalement en augmentant les niveaux de dopamine (DA), un neurotransmetteur qui joue un rГґle dans les voies de rГ©compense et le contrГґle moteur. Il agit en bloquant la liaison de l'adГ©nosine, qui est normalement prГ©sente dans le corps pendant le sommeil. Son utilisation principale est de traiter la somnolence diurne excessive associГ©e Г la narcolepsie. FDA), armodafinil-SR (SUN), crotone (canadien), Dristan, Intuniv, Modarest, Modavigil, Modavigil HBC (International), Modasyn , Obtechal, Rivalen, Sonata, et sous d'autres noms de marque dans d'autres pays.
modafinil france acheter Le modafinil a la capacitГ© d'occuper et d'activer les rГ©cepteurs de la dopamine, qui seraient impliquГ©s dans la production de dopamine, l'hormone du sommeil. Le modafinil semble agir en agissant sur la dopamine et en modulant les zones du cerveau impliquГ©es dans le cycle du sommeil. Le modafinil est Г©galement utilisГ© dans le traitement des personnes souffrant d'autres troubles qui provoquent une somnolence diurne excessive comme la dГ©pression, certains types de douleur et l'obГ©sitГ©. Il semble ГЄtre efficace contre les dГ©ficits cognitifs de la schizophrГ©nie, cependant, une Г©tude n'a pas soutenu son utilisation dans le traitement de la schizophrГ©nie. Il est Г©galement appelГ© Provigil, Generikum® Modafinil, Modalefenol et Modralift. Le nom chimique du modafinil est 2-[(dipropylamino)mГ©thyl]-1-benzothiophГЁne. Il est Г©galement commercialisГ© par certaines sociГ©tГ©s pharmaceutiques en Inde, en Chine, aux Г‰mirats arabes unis et au Pakistan comme somnifГЁre. Le modafinil est un dГ©rivГ© synthГ©tique du mГ©thylphГ©nidate : le mГ©dicament est constituГ© d'une phГ©nГ©thylamine et d'un groupe isopropylmГ©thyle. L'arrГЄt est recommandГ© dГЁs les premiers signes d'Г©ruption cutanГ©e ou de rГ©actions similaires. Le modafinil a Г©tГ© prescrit Г des doses de 100 Г 300 mg, bien que des doses plus Г©levГ©es allant jusqu'Г 400 mg ne soient pas rares. Les comprimГ©s de modafinil doivent ГЄtre avalГ©s entiers. Le modafinil peut ГЄtre pris avec les repas, car il contient de la diphenhydramine. Les symptГґmes comprennent une somnolence excessive, de la fatigue et une irritabilitГ© accrue. ГЂ une dose quotidienne moyenne de 400 Г 1200 mg, la concentration plasmatique efficace habituelle est d'environ 500 ng/mL.
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Il a été démontré qu'il augmente la vigilance et améliore les performances diurnes chez les personnes atteintes de narcolepsie, améliorant leur capacité à se concentrer et à accomplir des tâches. Le modafinil est utilisé pour traiter la somnolence diurne excessive chez les personnes souffrant de narcolepsie, d'apnée obstructive du sommeil et de travail posté. Bien que cette classification repose en grande partie sur des informations sur la façon dont le médicament est utilisé et son comportement dans un cadre contrôlé, l'American Society of Pharmacology and Experimental Therapeutics ne recommande pas de programmer Modafinil jusqu'à ce que davantage de recherches soient menées pour déterminer correctement son efficacité et son utilisation appropriée. Le modafinil perturbe cet équilibre d'adénosine, aidant les gens à rester vigilants. En 2009, une action en justice a été déposée contre Pfizer pour la commercialisation hors AMM du Modafinil. Les personnes qui utilisent le modafinil peuvent être exposées à un risque accru de symptômes de sevrage si elles arrêtent soudainement de le prendre, de sorte que les personnes doivent être étroitement surveillées si elles ont utilisé du modafinil dans le passé. Une fois l'éveil établi, le médicament semble avoir un effet soutenu qui cible les systèmes responsables du maintien de la vigilance. Cependant, ils ne sont pas aussi réalistes que les illusions visuelles qui font paraître des objets, des personnes ou des animaux plus grands ou plus petits ou qui ont changé de forme. Le modafinil est un stimulant favorisant l'éveil, également disponible en préparations à libération prolongée. Le médicament est efficace dans les deux conditions, mais fonctionne mieux dans les troubles du sommeil liés au travail posté. On ne sait pas exactement comment Modafinil fonctionne. On pense que le modafinil augmente l'éveil en stimulant ce système et qu'il réduit également la mélatonine, l'hormone induisant le sommeil dans le cerveau. Le modafinil induit l'éveil et augmente la vigilance en stimulant les récepteurs de la dopamine dans le système mésolimbique.
modafinil france acheter Le modafinil a Г©tГ© initialement dГ©veloppГ© comme agent anti-narcolepsie, et il a Г©tГ© approuvГ© par la Food and Drug Administration (FDA) en octobre 1996. Il peut Г©galement ГЄtre disponible sous forme de suspension et de sirop. Il est Г©galement utilisГ© pour prГ©venir la fatigue et la somnolence diurne excessive (EDS) chez les personnes atteintes de narcolepsie, et est parfois utilisГ© pour traiter d'autres troubles du sommeil. Il peut Г©galement provoquer des effets secondaires graves tels que l'anaphylaxie, l'Г©rythГЁme polymorphe, le syndrome de Stevens-Johnson et des effets secondaires potentiellement mortels tels que des convulsions, une pression artГ©rielle Г©levГ©e, des arythmies et une hypertrophie ventriculaire gauche. En raison du potentiel relativement faible de dГ©pendance et d'abus, il peut ГЄtre considГ©rГ© comme une alternative plus sГ»re aux autres mГ©dicaments stimulants, tels que les amphГ©tamines. Le modafinil est un stimulant non amphГ©tamine et non mГ©thamphГ©tamine qui agit Г la fois sur la recapture de la noradrГ©naline et de la sГ©rotonine ainsi que sur la libГ©ration de dopamine. Il est ne pas recommandГ© de modifier la posologie de Modafinil en fonction de votre Гўge ou de votre poids. Le modafinil a un effet stimulant, souvent euphorique et alertant sur le systГЁme nerveux central. Il contient un certain nombre de stimulants, notamment des amphГ©tamines, des benzyltropanes et des phГ©nГ©thylamines. L'augmentation des taux d'orexine peut ГЄtre impliquГ©e dans l'Г©lГ©vation des taux d'hypocrГ©tine, un neuropeptide favorisant l'Г©veil (orexine-A/hypocrГ©tine-1) et dans une diminution des mouvements oculaires rapides, la galanine, un neuropeptide favorisant le sommeil. Un examen de 2014 des Г©tudes sur les animaux a rГ©vГ©lГ© qu'il avait une efficacitГ© limitГ©e Г cette fin, mais un examen de 2017 des Г©tudes sur l'homme a rГ©vГ©lГ© que "le modafinil dГ©montre systГ©matiquement des effets cliniquement significatifs sur la vigilance, les performances cognitives et la fonction neuropsychologique".
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